Welcome to our
laboratory RESEARCH PAGE

Unlocking the mystery of cellular metabolism to understand and treat complex diseases

team_1

Dr. Thomas Pulinilkunnil

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
tpulinil@dal.ca

Nutrient regulation of lysosome metabolism, signaling and autophagy in health and disease; Amino acid biology...

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team_2

Dr. Petra C. Kienesberger

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
pkienesb@dal.ca

My research aims to uncover the interplay among bioactive lipid signaling and cellular and organismal...

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LATEST NEWS

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We are hiring!

Posted by Petra September 5, 2019

If you are passionate about studying the biology of nutrient metabolism then here is an...

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Congratulations to a successful PhD thesis defense, Kenneth! Very well done!

Posted by Petra August 27, 2019

Dr. Kenneth D’Souza delivered an excellent PhD thesis defense in Halifax on August 21, 2019!...

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Welcome to our lab, Wai!

Posted by Petra May 28, 2019

We are excited to announce that Ms. Wai Naing, who earned a BSc degree from...

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Congratulations to Mr. Logan Slade for being awarded Alexander Graham Bell Canada Graduate Scholarship!

Posted by THOMAS PULINILKUNNIL May 23, 2019

Heartfelt congratulations to Logan, a doctoral student in the Pulinilkunnil lab, for obtaining Alexander Graham...

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Congratulations to Purvi Trivedi for being awarded an NBHRF Travel Grant

Posted by THOMAS PULINILKUNNIL March 23, 2019

Congratulations to Purvi Trivedi for being awarded an NBHRF Travel Grant a to support her...

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LATEST PUBLICATIONS

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Role of branched-chain amino acid-catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis. Biswas D, Duffley L, Pulinilkunnil T. FASEB. 2019 May 14:fj201802842RR. doi: 10.1096/fj.201802842RR.

2019. May 23, 2019 Read More

Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study. Aguiar C, MacLeod J, Yip A, Melville S, Légaré JF, Pulinilkunnil T, Kienesberger P, Brunt K, Hassan A. BMJ Open. 2019 Mar 3;9(3):e023418. doi: 10.1136/bmjopen-2018-023418.

2019. April 2, 2019 Read More

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. D’Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. J Lipid Res. 2018 Oct;59(10):1805-1817. doi: 10.1194/jlr.M082008.

2018. August 14, 2018 Read More

Lysophosphatidic acid signaling in obesity and insulin resistance. D’Souza K, Paramel GV, Kienesberger PC. Nutrients. 2018 Mar 23;10(4). pii: E399.

2018. May 22, 2018 Read More

Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans. Brown A, Hossain I, Perez LJ, Nzirorera C, Tozer K, D’Souza K, Trivedi PC, Aguiar C, Yip AM, Shea J, Brunt KR, Legare JF, Hassan A, Pulinilkunnil T, Kienesberger PC. PLoS One. 2017 Dec 13;12(12):e0189402.

2017. October 22, 2017 Read More