Welcome to our
laboratory RESEARCH PAGE
Unlocking the mystery of cellular metabolism to understand and treat complex diseases
Dr. Thomas Pulinilkunnil
ProfessorDepartment of Biochemistry and Molecular Biology, Dalhousie University
tpulinil@dal.ca
Nutrient regulation of lysosome metabolism, signaling and autophagy in health and disease; Amino acid biology...
Dr. Petra C. Kienesberger
Associate ProfessorDepartment of Biochemistry and Molecular Biology, Dalhousie University
pkienesb@dal.ca
My research aims to uncover the interplay among bioactive lipid signaling and cellular and organismal...
LATEST NEWS
SEE ALLCongratulations to Ms Adithi Pisapati for being awarded a DalCREW graduate studentship!
Posted by Petra August 30, 2022 Read MoreCongratulations to Ms Anu Jose for being awarded a DalCREW graduate studentship!
Posted by Petra August 30, 2022 Read MoreCongratulations to Maggie Pickard on her successful MSc thesis defence!
Posted by Petra May 20, 2023 Read MoreLATEST PUBLICATIONS
SEE ALLLoss of transcription factor EB dysregulates the G1/S transition and DNA replication in mammary epithelial cells. Slade L, Biswas D, Kienesberger PC, Pulinilkunnil T. J Biol Chem. 2022;298(12):102692. doi: 10.1016/j.jbc.2022.102692. PMID: 36372230
2022. May 9, 2023
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Nanoparticle surface-enhanced Raman spectroscopy as a noninvasive, label-free tool to monitor hematological malignancy. Grieve S, Puvvada N, Phinyomark A, Russell K, Murugesan A, Zed E, Hassan A, Legare JF, Kienesberger PC, Pulinilkunnil T, Reiman T, Scheme E, Brunt KR. Nanomedicine (Lond).16(24):2175-2188. doi: 10.2217/nnm-2021-0076. PMID: 34547916
2021. May 9, 2023
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Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity. Biswas D, Slade L, Duffley L, Mueller N, Dao KT, Mercer A, Pakkiriswami S, El Hiani Y, Kienesberger PC, Pulinilkunnil T. Cell Death Discov. 2021 Sep 15;7(1):241. doi: 10.1038/s41420-021-00602-0. PMID: 34526485
2021. October 6, 2021
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