Welcome to our
laboratory RESEARCH PAGE

Unlocking the mystery of cellular metabolism to understand and treat complex diseases

Dr. Thomas Pulinilkunnil

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
tpulinil@dal.ca

Nutrient regulation of lysosome metabolism, signaling and autophagy in health and disease; Amino acid biology...

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Dr. Petra C. Kienesberger

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
pkienesb@dal.ca

My research aims to uncover the interplay among bioactive lipid signaling and cellular and organismal...

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LATEST NEWS

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Come join us at the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax, Canada, from 21 to 24 June 2020

Posted by Petra November 14, 2019

https://shvm2020.azuleon.org/welcome.php

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Congratulations to Ms. Angella Mercer for her poster prize (1st place) at the New Brunswick Health Research conference in Nov 2019!

Posted by Petra November 14, 2019

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We celebrated Dr. D’Souza’s achievements at the Dalhousie University fall convocation

Posted by Petra October 9, 2019

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We are hiring!

Posted by Petra September 5, 2019

If you are passionate about studying the biology of nutrient metabolism then here is an...

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Congratulations to a successful PhD thesis defense, Kenneth! Very well done!

Posted by Petra August 27, 2019

Dr. Kenneth D’Souza delivered an excellent PhD thesis defense in Halifax on August 21, 2019!...

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LATEST PUBLICATIONS

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Role of branched-chain amino acid-catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis. Biswas D, Duffley L, Pulinilkunnil T. FASEB. 2019 May 14:fj201802842RR. doi: 10.1096/fj.201802842RR.

2019. May 23, 2019 Read More

Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study. Aguiar C, MacLeod J, Yip A, Melville S, Légaré JF, Pulinilkunnil T, Kienesberger P, Brunt K, Hassan A. BMJ Open. 2019 Mar 3;9(3):e023418. doi: 10.1136/bmjopen-2018-023418.

2019. April 2, 2019 Read More

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. D’Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. J Lipid Res. 2018 Oct;59(10):1805-1817. doi: 10.1194/jlr.M082008.

2018. August 14, 2018 Read More

Lysophosphatidic acid signaling in obesity and insulin resistance. D’Souza K, Paramel GV, Kienesberger PC. Nutrients. 2018 Mar 23;10(4). pii: E399.

2018. May 22, 2018 Read More

Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans. Brown A, Hossain I, Perez LJ, Nzirorera C, Tozer K, D’Souza K, Trivedi PC, Aguiar C, Yip AM, Shea J, Brunt KR, Legare JF, Hassan A, Pulinilkunnil T, Kienesberger PC. PLoS One. 2017 Dec 13;12(12):e0189402.

2017. October 22, 2017 Read More