Welcome to our
laboratory RESEARCH PAGE

Unlocking the mystery of cellular metabolism to understand and treat complex diseases

Dr. Thomas Pulinilkunnil

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
tpulinil@dal.ca

Nutrient regulation of lysosome metabolism, signaling and autophagy in health and disease; Amino acid biology...

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Dr. Petra C. Kienesberger

Associate Professor
Department of Biochemistry and Molecular Biology, Dalhousie University
pkienesb@dal.ca

My research aims to uncover the interplay among bioactive lipid signaling and cellular and organismal...

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LATEST NEWS

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Welcome to the lab, Dr. Sundaram Pakkiriswami!

Posted by Petra April 28, 2020

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We are grateful for the NSERC Discovery Grants awarded to the Pulinilkunnil and Kienesberger labs. A big thanks to all the people in the lab who made this possible.

Posted by Petra April 28, 2020

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Come join us at the 18th Annual Meeting of the Society for Heart and Vascular Metabolism (SHVM), to be held in the vibrant and charming seaport city, Halifax, Canada, from 21 to 24 June 2020

Posted by Petra November 14, 2019

https://shvm2020.azuleon.org/welcome.php

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Congratulations to Ms. Angella Mercer for her poster prize (1st place) at the New Brunswick Health Research conference in Nov 2019!

Posted by Petra November 14, 2019

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We celebrated Dr. D’Souza’s achievements at the Dalhousie University fall convocation

Posted by Petra October 9, 2019

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LATEST PUBLICATIONS

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Lysosomal Biology and Function: Modern View of Cellular Debris Bin. Trivedi PC, Bartlett JJ, Pulinilkunnil T. Cells. 2020 May 4;9(5). pii: E1131. doi: 10.3390/cells9051131. Review.

2020. May 10, 2020 Read More

Whey Peptides Stimulate Differentiation and Lipid Metabolism in Adipocytes and Ameliorate Lipotoxicity-Induced Insulin Resistance in Muscle Cells. D’Souza K, Mercer A ,Mawhinney H, Pulinilkunnil T, Udenigwe CC, Kienesberger PC. Nutrients 2020, 12(2), 425; https://doi.org/10.3390/nu12020425

2020. February 6, 2020 Read More

A Lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells. Slade L, Biswas D, Ihionu F, El Hiani Y, Kienesberger PC, Pulinilkunnil T. Biochem J. 2020 Jan 17;477(1):137-160. doi: 10.1042/BCJ20190596.

2020. January 17, 2020 Read More

Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery. Aguiar CM, Gawdat K, Legere S, Marshall J, Hassan A, Kienesberger PC, Pulinilkunnil T, Castonguay M, Brunt KR, Legare JF. J Transl Med. 2019 Dec 10;17(1):413. doi: 10.1186/s12967-019-02162-5.

2019. December 15, 2019 Read More

Editorial: Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease. Pulinilkunnil T, Kienesberger P, Nagendran J. Front Cardiovasc Med. 2019 Jul 12;6:97. doi: 10.3389/fcvm.2019.00097. eCollection 2019

2019. December 15, 2019 Read More