Palmitate and a combination of glucose palmitate decrease lysosomal content and cathepsin activity in neonatal rat cardiomyocytes. Proteotoxic basis for obesity related cardiomyopathy involves loss of TFEB action and suppressed autophagy.
Palmitate and a combination of glucose palmitate decrease lysosomal content and cathepsin activity in neonatal rat cardiomyocytes. Proteotoxic basis for obesity related cardiomyopathy involves loss of TFEB action and suppressed autophagy.